Director: Eric P. Hoffman, PhD
Co-Director: Robert Leshner, M.D.
The Wellstone Muscular Dystrophy Center of Washington DC is housed within Children’s National Medical Center, one of the top 10 children’s hospitals in the US.
The Center is highly interdisciplinary, including physicians, molecular geneticists, computer scientists, veterinarians, and genetic counselors, all with specialized expertise in muscular dystrophy.
The Center incorporates and integrates an international clinical trial coordinating center (www.cinrgresearch.org), and state-of-the-art genomics, proteomics, and mRNA profiling research.
The focus of the research in the 5 yr Center grant (2005-2010) is specifically on Duchenne muscular dystrophy. A press release on the awarding of the Center can be found at the following link.
The abstract of the overall grant, three research projects, and three core support facilities can be found at the following links:
Overall Goal of the Center
History of the Center
Project 1: Genetic Modifiers of Duchenne muscular dystrophy.
Project 2. TGFbeta and NFkB pathways in progression of DMD.
Project 3. Stem cells and failure of regeneration in DMD.
Core A. Administrative
Core B. CINRG Human Clinical Trial Core
CINRG Clinical Trials
Core C. Bioinformatics and Computing Core
Recent Publications of Center