Publications of Center Personnel (since 2005)
Chen, Yi-Wen
1: Chen YW, Shi R, Geraci N, Shrestha S, Gordish-Dressman H, Pachman LM.
Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis.
BMC Immunol. 2008 Jul 31;9:43.
PMID: 18671865 [PubMed - indexed for MEDLINE]
2: Dixit M, Ansseau E, Tassin A, Winokur S, Shi R, Qian H, Sauvage S, Mattéotti C, van Acker AM, Leo O, Figlewicz D, Barro M, Laoudj-Chenivesse D, Belayew A,
Coppée F, Chen YW.
DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.
Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18157-62. Epub 2007 Nov 5.
PMID: 17984056 [PubMed - indexed for MEDLINE]
3: Chen YW, Gregory CM, Scarborough MT, Shi R, Walter GA, Vandenborne K.
Transcriptional pathways associated with skeletal muscle disuse atrophy in humans.
Physiol Genomics. 2007 Nov 14;31(3):510-20. Epub 2007 Sep 5.
PMID: 17804603 [PubMed - indexed for MEDLINE]
4: Xuan J, Wang Y, Dong Y, Feng Y, Wang B, Khan J, Bakay M, Wang Z, Pachman L, Winokur S, Chen YW, Clarke R, Hoffman E.
Gene selection for multiclass prediction by weighted fisher criterion.
EURASIP J Bioinform Syst Biol. 2007:64628.
PMID: 17713593 [PubMed - in process]
5: Kostek MC, Chen YW, Cuthbertson DJ, Shi R, Fedele MJ, Esser KA, Rennie MJ.
Gene expression responses over 24 h to lengthening and shortening contractions in human muscle: major changes in CSRP3, MUSTN1, SIX1, and FBXO32.
Physiol Genomics. 2007 Sep 19;31(1):42-52. Epub 2007 May 22.
PMID: 17519359 [PubMed - indexed for MEDLINE]
6: Urso ML, Scrimgeour AG, Chen YW, Thompson PD, Clarkson PM.
Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components.
J Appl Physiol. 2006 Oct;101(4):1136-48. Epub 2006 Jun 8.
PMID: 16763108 [PubMed - indexed for MEDLINE]
7: Nagaraju K, Rider LG, Fan C, Chen YW, Mitsak M, Rawat R, Patterson K, Grundtman C, Miller FW, Plotz PH, Hoffman E, Lundberg IE.
Endothelial cell activation and neovascularization are prominent in dermatomyositis.
J Autoimmune Dis. 2006 Feb 20;3:2.
PMID: 16504012 [PubMed]
8: Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, Zhao P, Sartorelli V, Seo J, Pegoraro E, Angelini C, Shneiderman B, Escolar D, Chen YW, Winokur ST, Pachman
LM, Fan C, Mandler R, Nevo Y, Gordon E, Zhu Y, Dong Y, Wang Y, Hoffman EP.
Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration.
Brain. 2006 Apr;129(Pt 4):996-1013. Epub 2006 Feb 14.
PMID: 16478798 [PubMed - indexed for MEDLINE]
9: Nagaraju K, Casciola-Rosen L, Lundberg I, Rawat R, Cutting S, Thapliyal R, Chang J, Dwivedi S, Mitsak M, Chen YW, Plotz P, Rosen A, Hoffman E, Raben N.
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction.
Arthritis Rheum. 2005 Jun;52(6):1824-35.
PMID: 15934115 [PubMed - indexed for MEDLINE]
Nagaraju, Kanneboyina
1: Kesari A, Fukuda M, Knoblach S, Bashir R, Nader GA, Rao D, Nagaraju K, Hoffman EP.
Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset.
Am J Pathol. 2008 Nov;173(5):1476-87. Epub 2008 Oct 2.
PMID: 18832576 [PubMed - in process]
2: Wu B, Moulton HM, Iversen PL, Jiang J, Li J, Li J, Spurney CF, Sali A, Guerron AD, Nagaraju K, Doran T, Lu P, Xiao X, Lu QL.
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14814-9. Epub 2008 Sep 19.
PMID: 18806224 [PubMed - indexed for MEDLINE]
3: Grounds MD, Radley HG, Lynch GS, Nagaraju K, De Luca A.
Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy.
Neurobiol Dis. 2008 Jul;31(1):1-19. Epub 2008 Apr 9. Review.
PMID: 18499465 [PubMed - indexed for MEDLINE]
4: Spurney CF, Knoblach S, Pistilli EE, Nagaraju K, Martin GR, Hoffman EP.
Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart.
Neuromuscul Disord. 2008 May;18(5):371-81. Epub 2008 Apr 25.
PMID: 18440230 [PubMed - indexed for MEDLINE]
5: Mintz M, Vanderver A, Brown KJ, Lin J, Wang Z, Kaneski C, Schiffmann R, Nagaraju K, Hoffman EP, Hathout Y.
Time series proteome profiling to study endoplasmic reticulum stress response.
J Proteome Res. 2008 Jun;7(6):2435-44. Epub 2008 Apr 25.
PMID: 18435558 [PubMed - indexed for MEDLINE]
6: Nagaraju K, Rawat R, Veszelovszky E, Thapliyal R, Kesari A, Sparks S, Raben N, Plotz P, Hoffman EP.
Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.
Am J Pathol. 2008 Mar;172(3):774-85. Epub 2008 Feb 14.
PMID: 18276788 [PubMed - indexed for MEDLINE]
7: Freishtat RJ, Mojgani B, Nazemzadeh M, Nagaraju K, Hoffman EP.
NKG2A inhibits TH2 cell effector function in vitro.
BMC Pulm Med. 2007 Oct 10;7:14.
PMID: 17927829 [PubMed - indexed for MEDLINE]
8: Raben N, Takikita S, Pittis MG, Bembi B, Marie SK, Roberts A, Page L, KishnaniPS, Schoser BG, Chien YH, Ralston E, Nagaraju K, Plotz PH.
Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand...
Autophagy. 2007 Nov-Dec;3(6):546-52. Epub 2007 Jun 15.
PMID: 17592248 [PubMed - indexed for MEDLINE]
9: Yokota T, Pistilli E, Duddy W, Nagaraju K.
Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy.
Expert Opin Biol Ther. 2007 Jun;7(6):831-42. Review.
PMID: 17555369 [PubMed - indexed for MEDLINE]
10: Shelton GD, Hoffman EP, Ghimbovschi S, Peters IR, Day MJ, Mullins M, Moore PF, Nagaraju K.
Immunopathogenic pathways in canine inflammatory myopathies resemble human myositis.
Vet Immunol Immunopathol. 2006 Sep 15;113(1-2):200-14. Epub 2006 Jun 23.
PMID: 16797723 [PubMed - indexed for MEDLINE]
11: Lamason R, Zhao P, Rawat R, Davis A, Hall JC, Chae JJ, Agarwal R, Cohen P, Rosen A, Hoffman EP, Nagaraju K.
Sexual dimorphism in immune response genes as a function of puberty.
BMC Immunol. 2006 Feb 22;7:2.
PMID: 16504066 [PubMed - indexed for MEDLINE]
12: Nagaraju K, Rider LG, Fan C, Chen YW, Mitsak M, Rawat R, Patterson K, Grundtman C, Miller FW, Plotz PH, Hoffman E, Lundberg IE.
Endothelial cell activation and neovascularization are prominent in dermatomyositis.
J Autoimmune Dis. 2006 Feb 20;3:2.
PMID: 16504012 [PubMed]
13: Nagaraju K.
Role of major histocompatibility complex class I molecules in autoimmune myositis.
Curr Opin Rheumatol. 2005 Nov;17(6):725-30. Review.
PMID: 16224250 [PubMed - indexed for MEDLINE]
14: Nagaraju K, Casciola-Rosen L, Lundberg I, Rawat R, Cutting S, Thapliyal R, Chang J, Dwivedi S, Mitsak M, Chen YW, Plotz P, Rosen A, Hoffman E, Raben N.
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction.
Arthritis Rheum. 2005 Jun;52(6):1824-35.
PMID: 15934115 [PubMed - indexed for MEDLINE]
15: Casciola-Rosen L, Nagaraju K, Plotz P, Wang K, Levine S, Gabrielson E, Corse A, Rosen A.
Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy.
J Exp Med. 2005 Feb 21;201(4):591-601.
PMID: 15728237 [PubMed - indexed for MEDLINE]
16: Raben N, Fukuda T, Gilbert AL, de Jong D, Thurberg BL, Mattaliano RJ, Meikle P, Hopwood JJ, Nagashima K, Nagaraju K, Plotz PH.
Replacing acid alpha-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers.
Mol Ther. 2005 Jan;11(1):48-56.
PMID: 15585405 [PubMed - indexed for MEDLINE]
Partridge, Terry A
1: Isman O, Roberts ML, Morgan JE, Graham IR, Goldring K, Lawrence-Watt DJ, Lu QL, Dunckley MG, Porter AC, Partridge TA, Dickson G.
Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration.
Hum Gene Ther. 2008 Oct;19(10):1000-8.
PMID: 18788904 [PubMed - in process]
2: Isman O, Roberts M, Morgan J, Graham IR, Goldring K, Watt DJ, Lu Q, Dunckley MG, Porter AC, Partridge TA, Dickson G.
Adenovirus-based targeting in myoblasts is hampered by non-homologous vector integration.
Hum Gene Ther. 2008 Aug 5. [Epub ahead of print]
PMID: 18681770 [PubMed - as supplied by publisher]
3: Collins CA, Zammit PS, Ruiz AP, Morgan JE, Partridge TA.
A population of myogenic stem cells that survives skeletal muscle aging.
Stem Cells. 2007 Apr;25(4):885-94. Epub 2007 Jan 11.
PMID: 17218401 [PubMed - indexed for MEDLINE]
4: Golding JP, Calderbank E, Partridge TA, Beauchamp JR.
Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence.
Exp Cell Res. 2007 Jan 15;313(2):341-56. Epub 2006 Oct 26.
PMID: 17123512 [PubMed - indexed for MEDLINE]
5: Zammit PS, Partridge TA, Yablonka-Reuveni Z.
The skeletal muscle satellite cell: the stem cell that came in from the cold.
J Histochem Cytochem. 2006 Nov;54(11):1177-91. Epub 2006 Aug 9. Review.
PMID: 16899758 [PubMed - indexed for MEDLINE]
6: Nagata Y, Partridge TA, Matsuda R, Zammit PS.
Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling.
J Cell Biol. 2006 Jul 17;174(2):245-53.
PMID: 16847102 [PubMed - indexed for MEDLINE]
7: Yokota T, Lu QL, Morgan JE, Davies KE, Fisher R, Takeda S, Partridge TA.
Expansion of revertant fibers in dystrophic mdx muscles reflects activity of muscle precursor cells and serves as an index of muscle regeneration.
J Cell Sci. 2006 Jul 1;119(Pt 13):2679-87. Epub 2006 Jun 6.
PMID: 16757519 [PubMed - indexed for MEDLINE]
8: Zammit PS, Relaix F, Nagata Y, Ruiz AP, Collins CA, Partridge TA, Beauchamp JR.
Pax7 and myogenic progression in skeletal muscle satellite cells.
J Cell Sci. 2006 May 1;119(Pt 9):1824-32. Epub 2006 Apr 11.
PMID: 16608873 [PubMed - indexed for MEDLINE]
9: Tam JL, Triantaphyllopoulos K, Todd H, Raguz S, de Wit T, Morgan JE, Partridge TA, Makrinou E, Grosveld F, Antoniou M.
The human desmin locus: gene organization and LCR-mediated transcriptional control.
Genomics. 2006 Jun;87(6):733-46. Epub 2006 Mar 20.
PMID: 16545539 [PubMed - indexed for MEDLINE]
10: Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL.
Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology.
Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29.
PMID: 16444267 [PubMed - indexed for MEDLINE]
11: Collins CA, Partridge TA.
Self-renewal of the adult skeletal muscle satellite cell.
Cell Cycle. 2005 Oct;4(10):1338-41. Epub 2005 Oct 23.
PMID: 16177569 [PubMed - indexed for MEDLINE]
12: Collins CA, Olsen I, Zammit PS, Heslop L, Petrie A, Partridge TA, Morgan JE.
Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche.
Cell. 2005 Jul 29;122(2):289-301.
PMID: 16051152 [PubMed - indexed for MEDLINE]
Wang, Zuyi
1: Zhu Y, Li H, Miller DJ, Wang Z, Xuan J, Clarke R, Hoffman EP, Wang Y.
caBIG VISDA: modeling, visualization, and discovery for cluster analysis of genomic data.
BMC Bioinformatics. 2008 Sep 18;9:383.
PMID: 18801195 [PubMed - in process]
2: Zhu Y, Wang Z, Miller DJ, Clarke R, Xuan J, Hoffman EP, Wang Y.
A ground truth based comparative study on clustering of gene expression data.
Front Biosci. 2008 May 1;13:3839-49. Review.
PMID: 18508478 [PubMed - indexed for MEDLINE]
3: Mintz M, Vanderver A, Brown KJ, Lin J, Wang Z, Kaneski C, Schiffmann R, Nagaraju K, Hoffman EP, Hathout Y.
Time series proteome profiling to study endoplasmic reticulum stress response.
J Proteome Res. 2008 Jun;7(6):2435-44. Epub 2008 Apr 25.
PMID: 18435558 [PubMed - indexed for MEDLINE]
4: Zhu Y, Wang Z, Feng Y, Xuan J, Miller DJ, Hoffman EP, Wang Y.
Phenotypic-specific gene module discovery using a diagnostic tree and caBIG VISDA.
Conf Proc IEEE Eng Med Biol Soc. 2006;1:5767-70.
PMID: 17946331 [PubMed - indexed for MEDLINE]
5: Xuan J, Wang Y, Dong Y, Feng Y, Wang B, Khan J, Bakay M, Wang Z, Pachman L, Winokur S, Chen YW, Clarke R, Hoffman E.
Gene selection for multiclass prediction by weighted fisher criterion.
EURASIP J Bioinform Syst Biol. 2007:64628.
PMID: 17713593 [PubMed - in process]
6: Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, Zhao P, Sartorelli V, Seo J, Pegoraro E, Angelini C, Shneiderman B, Escolar D, Chen YW, Winokur ST, Pachman LM, Fan C, Mandler R, Nevo Y, Gordon E, Zhu Y, Dong Y, Wang Y, Hoffman EP.
Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration.
Brain. 2006 Apr;129(Pt 4):996-1013. Epub 2006 Feb 14.
PMID: 16478798 [PubMed - indexed for MEDLINE]
7: Wang Z, Wang Y, Xuan J, Dong Y, Bakay M, Feng Y, Clarke R, Hoffman EP.
Optimized multilayer perceptrons for molecular classification and diagnosis using genomic data.
Bioinformatics. 2006 Mar 15;22(6):755-61. Epub 2006 Jan 10.
PMID: 16403791 [PubMed - indexed for MEDLINE]
Hoffman, Eric P
1: Kesari A, Fukuda M, Knoblach S, Bashir R, Nader GA, Rao D, Nagaraju K, Hoffman EP.
Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset.
Am J Pathol. 2008 Nov;173(5):1476-87. Epub 2008 Oct 2.
PMID: 18832576 [PubMed - in process]
2: Zhu Y, Li H, Miller DJ, Wang Z, Xuan J, Clarke R, Hoffman EP, Wang Y.
caBIG VISDA: modeling, visualization, and discovery for cluster analysis of genomic data.
BMC Bioinformatics. 2008 Sep 18;9:383.
PMID: 18801195 [PubMed - in process]
3: Almon RR, Yang E, Lai W, Androulakis IP, Ghimbovschi S, Hoffman EP, Jusko WJ, Dubois DC.
Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle.
Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1031-47. Epub 2008 Jul 30.
PMID: 18667713 [PubMed - in process]
4: Zoeller RF, Ryan ED, Gordish-Dressman H, Price TB, Seip RL, Angelopoulos TJ, Moyna NM, Gordon PM, Thompson PD, Hoffman EP.
Allometric scaling of isometric biceps strength in adult females and the effect of body mass index.
Eur J Appl Physiol. 2008 Nov;104(4):701-10. Epub 2008 Jul 22.
PMID: 18648848 [PubMed - in process]
5: Vanderver A, Hathout Y, Maletkovic J, Gordon ES, Mintz M, Timmons M, Hoffman EP, Horzinski L, Niel F, Fogli A, Boespflug-Tanguy O, Schiffmann R.
Sensitivity and specificity of decreased CSF asialotransferrin for eIF2B-related disorder.
Neurology. 2008 Jun 3;70(23):2226-32.
PMID: 18519871 [PubMed - indexed for MEDLINE]
6: Pistilli EE, Devaney JM, Gordish-Dressman H, Bradbury MK, Seip RL, Thompson PD, Angelopoulos TJ, Clarkson PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Gordon PM, Hoffman EP.
Interleukin-15 and interleukin-15R alpha SNPs and associations with muscle, bone, and predictors of the metabolic syndrome.
Cytokine. 2008 Jul;43(1):45-53. Epub 2008 Jun 2.
PMID: 18514540 [PubMed - indexed for MEDLINE]
7: Zhu Y, Wang Z, Miller DJ, Clarke R, Xuan J, Hoffman EP, Wang Y.
A ground truth based comparative study on clustering of gene expression data.
Front Biosci. 2008 May 1;13:3839-49. Review.
PMID: 18508478 [PubMed - indexed for MEDLINE]
8: Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V.
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt.
Dev Cell. 2008 May;14(5):661-73.
PMID: 18477450 [PubMed - indexed for MEDLINE]
9: Spurney CF, Knoblach S, Pistilli EE, Nagaraju K, Martin GR, Hoffman EP.
Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart.
Neuromuscul Disord. 2008 May;18(5):371-81. Epub 2008 Apr 25.
PMID: 18440230 [PubMed - indexed for MEDLINE]
10: Mintz M, Vanderver A, Brown KJ, Lin J, Wang Z, Kaneski C, Schiffmann R, Nagaraju K, Hoffman EP, Hathout Y.
Time series proteome profiling to study endoplasmic reticulum stress response.
J Proteome Res. 2008 Jun;7(6):2435-44. Epub 2008 Apr 25.
PMID: 18435558 [PubMed - indexed for MEDLINE]
11: Kesari A, Pirra LN, Bremadesam L, McIntyre O, Gordon E, Dubrovsky AL, Viswanathan V, Hoffman EP.
Integrated DNA, cDNA, and protein studies in Becker muscular dystrophy show high exception to the reading frame rule.
Hum Mutat. 2008 May;29(5):728-37.
PMID: 18348289 [PubMed - indexed for MEDLINE]
12: Hayward LJ, Kim JS, Lee MY, Zhou H, Kim JW, Misra K, Salajegheh M, Wu FF, Matsuda C, Reid V, Cros D, Hoffman EP, Renaud JM, Cannon SC, Brown RH Jr.
Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness.
J Clin Invest. 2008 Apr;118(4):1437-49.
PMID: 18317596 [PubMed - indexed for MEDLINE]
13: Nagaraju K, Rawat R, Veszelovszky E, Thapliyal R, Kesari A, Sparks S, Raben N, Plotz P, Hoffman EP.
Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatoryonset of limb-girdle muscular dystrophy 2B.
Am J Pathol. 2008 Mar;172(3):774-85. Epub 2008 Feb 14.
PMID: 18276788 [PubMed - indexed for MEDLINE]
14: Yao Z, Hoffman EP, Ghimbovschi S, Dubois DC, Almon RR, Jusko WJ.
Mathematical modeling of corticosteroid pharmacogenomics in rat muscle following acute and chronic methylprednisolone dosing.
Mol Pharm. 2008 Mar-Apr;5(2):328-39. Epub 2008 Feb 14.
PMID: 18271548 [PubMed - indexed for MEDLINE]
15: Maletkovic J, Schiffmann R, Gorospe JR, Gordon ES, Mintz M, Hoffman EP, Alper G, Lynch DR, Singhal BS, Harding C, Amartino H, Brown CM, Chan A, Renaud D, Geraghty M, Jensen L, Senbil N, Kadom N, Nazarian J, Yuanjian Feng, Zuyi Wang, Hartka T, Morizono H, Vanderver A.
Genetic and clinical heterogeneity in eIF2B-related disorder.
J Child Neurol. 2008 Feb;23(2):205-15.
PMID: 18263758 [PubMed - indexed for MEDLINE]
16: Lichter-Konecki U, Mangin JM, Gordish-Dressman H, Hoffman EP, Gallo V.
Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo.
Glia. 2008 Mar;56(4):365-77.
PMID: 18186079 [PubMed - indexed for MEDLINE]
17: Ramser J, Ahearn ME, Lenski C, Yariz KO, Hellebrand H, von Rhein M, Clark RD, Schmutzler RK, Lichtner P, Hoffman EP, Meindl A, Baumbach-Reardon L.
Rare missense and synonymous variants in UBE1 are associated with X-linked infantile spinal muscular atrophy.
Am J Hum Genet. 2008 Jan;82(1):188-93.
PMID: 18179898 [PubMed - indexed for MEDLINE]
18: Hoffman EP.
Skipping toward personalized molecular medicine.
N Engl J Med. 2007 Dec 27;357(26):2719-22. No abstract available.
PMID: 18160693 [PubMed - indexed for MEDLINE]
19: Di Padova M, Caretti G, Zhao P, Hoffman EP, Sartorelli V.
MyoD acetylation influences temporal patterns of skeletal muscle gene expression.
J Biol Chem. 2007 Dec 28;282(52):37650-9. Epub 2007 Oct 27.
PMID: 17965412 [PubMed - indexed for MEDLINE]
20: Gong T, Zhu Y, Xuan J, Li H, Clarke R, Hoffman EP, Wang Y.
Latent variable and nICA modeling of pathway gene module composite.
Conf Proc IEEE Eng Med Biol Soc. 2006;1:5872-5.
PMID: 17946342 [PubMed - indexed for MEDLINE]
21: Zhu Y, Wang Z, Feng Y, Xuan J, Miller DJ, Hoffman EP, Wang Y.
Phenotypic-specific gene module discovery using a diagnostic tree and caBIG VISDA.
Conf Proc IEEE Eng Med Biol Soc. 2006;1:5767-70.
PMID: 17946331 [PubMed - indexed for MEDLINE]
22: Freishtat RJ, Mojgani B, Nazemzadeh M, Nagaraju K, Hoffman EP.
NKG2A inhibits TH2 cell effector function in vitro.
BMC Pulm Med. 2007 Oct 10;7:14.
PMID: 17927829 [PubMed - indexed for MEDLINE]
23: Uthurralt J, Gordish-Dressman H, Bradbury M, Tesi-Rocha C, Devaney J, Harmon B, Reeves EK, Brandoli C, Hansen BC, Seip RL, Thompson PD, Price TB, Angelopoulos TJ, Clarkson PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Gordon PM, Hoffman EP.
PPARalpha L162V underlies variation in serum triglycerides and subcutaneous fat volume in young males.
BMC Med Genet. 2007 Aug 16;8:55.
PMID: 17705849 [PubMed - indexed for MEDLINE]
24: Kostek MA, Pescatello LS, Seip RL, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Thompson PD, Hoffman EP, Price TB.
Subcutaneous fat alterations resulting from an upper-body resistance training program.
Med Sci Sports Exerc. 2007 Jul;39(7):1177-85.
PMID: 17596787 [PubMed - indexed for MEDLINE]
25: Zoeller RF, Ryan ED, Gordish-Dressman H, Price TB, Seip RL, Angelopoulos TJ, Moyna NM, Gordon PM, Thompson PD, Hoffman EP.
Allometric scaling of biceps strength before and after resistance training in men.
Med Sci Sports Exerc. 2007 Jun;39(6):1013-9.
PMID: 17545893 [PubMed - indexed for MEDLINE]
26: Pescatello LS, Kelsey BK, Price TB, Seip RL, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Gordish-Dressman HA, Bilbie SM, Thompson PD, Hoffman EP.
The muscle strength and size response to upper arm, unilateral resistance training among adults who are overweight and obese.
J Strength Cond Res. 2007 May;21(2):307-13.
PMID: 17530988 [PubMed - indexed for MEDLINE]
27: Almon RR, DuBois DC, Yao Z, Hoffman EP, Ghimbovschi S, Jusko WJ.
Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens.
Physiol Genomics. 2007 Aug 20;30(3):282-99. Epub 2007 May 1.
PMID: 17473217 [PubMed - indexed for MEDLINE]
28: Yao Z, Zhao B, Hoffman EP, Ghimbovschi S, DuBois DC, Almon RR, Jusko WJ.
Application of scaling factors in simultaneous modeling of microarray data from diverse chips.
Pharm Res. 2007 Apr;24(4):643-9. Epub 2007 Feb 21.
PMID: 17318415 [PubMed - indexed for MEDLINE]
29: Nazarian J, Hathout Y, Vertes A, Hoffman EP.
The proteome survey of an electricity-generating organ (Torpedo californica electric organ).
Proteomics. 2007 Feb;7(4):617-27.
PMID: 17309107 [PubMed - indexed for MEDLINE]
30: Pistilli EE, Gordish-Dressman H, Seip RL, Devaney JM, Thompson PD, Price TB, Angelopoulos TJ, Clarkson PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Hoffman EP, Gordon PM.
Resistin polymorphisms are associated with muscle, bone, and fat phenotypes in white men and women.
Obesity (Silver Spring). 2007 Feb;15(2):392-402.
PMID: 17299113 [PubMed - indexed for MEDLINE]
31: Devaney JM, Hoffman EP, Gordish-Dressman H, Kearns A, Zambraski E, Clarkson PM.
IGF-II gene region polymorphisms related to exertional muscle damage.
J Appl Physiol. 2007 May;102(5):1815-23. Epub 2007 Feb 8.
PMID: 17289909 [PubMed - indexed for MEDLINE]
32: Massaro D, Alexander E, Reiland K, Hoffman EP, Massaro GD, Clerch LB.
Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction.
Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1313-26. Epub 2007 Jan 19.
PMID: 17237152 [PubMed - indexed for MEDLINE]
33: Dressman D, Ahearn ME, Yariz KO, Basterrecha H, Martínez F, Palau F, Barmada MM, Clark RD, Meindl A, Wirth B, Hoffman EP, Baumbach-Reardon L.
X-linked infantile spinal muscular atrophy: clinical definition and molecular mapping.
Genet Med. 2007 Jan;9(1):52-60.
PMID: 17224690 [PubMed - indexed for MEDLINE]
34: Hittel DS, Hathout Y, Hoffman EP.
Proteomics and systems biology in exercise and sport sciences research.
Exerc Sport Sci Rev. 2007 Jan;35(1):5-11. Review.
PMID: 17211187 [PubMed - indexed for MEDLINE]
35: Sun L, Gorospe JR, Hoffman EP, Rao AK.
Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/RUNX1 mutation: insights from platelet expression profiling.
J Thromb Haemost. 2007 Jan;5(1):146-54. Epub 2006 Oct 18.
PMID: 17059412 [PubMed - indexed for MEDLINE]
36: An E, Lu X, Flippin J, Devaney JM, Halligan B, Hoffman EP, Strunnikova N, Csaky K, Hathout Y.
Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors.
J Proteome Res. 2006 Oct;5(10):2599-610. Erratum in: J Proteome Res. 2007 Apr;6(4):1615. Strunnikova, Nataly [added]; Hoffman, Eric [corrected to Hoffman, Eric P].
PMID: 17022631 [PubMed - indexed for MEDLINE]
37: Caretti G, Schiltz RL, Dilworth FJ, Di Padova M, Zhao P, Ogryzko V, Fuller-Pace FV, Hoffman EP, Tapscott SJ, Sartorelli V.
The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.
Dev Cell. 2006 Oct;11(4):547-60.
PMID: 17011493 [PubMed - indexed for MEDLINE]
38: Bonifati DM, Witchel SF, Ermani M, Hoffman EP, Angelini C, Pegoraro E.
The glucocorticoid receptor N363S polymorphism and steroid response in Duchenne dystrophy.
J Neurol Neurosurg Psychiatry. 2006 Oct;77(10):1177-9.
PMID: 16980656 [PubMed - indexed for MEDLINE]
39: Seo J, Hoffman EP.
Probe set algorithms: is there a rational best bet?
BMC Bioinformatics. 2006 Aug 30;7:395.
PMID: 16942624 [PubMed - indexed for MEDLINE]
40: Park JJ, Berggren JR, Hulver MW, Houmard JA, Hoffman EP.
GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle.
Physiol Genomics. 2006 Oct 11;27(2):114-21. Epub 2006 Jul 18.
PMID: 16849634 [PubMed - indexed for MEDLINE]
41: Shelton GD, Hoffman EP, Ghimbovschi S, Peters IR, Day MJ, Mullins M, Moore PF, Nagaraju K.
Immunopathogenic pathways in canine inflammatory myopathies resemble human myositis.
Vet Immunol Immunopathol. 2006 Sep 15;113(1-2):200-14. Epub 2006 Jun 23.
PMID: 16797723 [PubMed - indexed for MEDLINE]
42: Pescatello LS, Kostek MA, Gordish-Dressman H, Thompson PD, Seip RL, Price TB, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Devaney JM, Hoffman EP.
ACE ID genotype and the muscle strength and size response to unilateral resistance training.
Med Sci Sports Exerc. 2006 Jun;38(6):1074-81.
PMID: 16775548 [PubMed - indexed for MEDLINE]
43: Hoffman EP, Escolar D.
Translating mighty mice into neuromuscular therapeutics: is bigger muscle better?
Am J Pathol. 2006 Jun;168(6):1775-8. No abstract available.
PMID: 16723694 [PubMed - indexed for MEDLINE]
44: Freishtat RJ, Mitchell LW, Ghimbovschi SD, Meyers SB, Hoffman EP.
NKG2A and CD56 are coexpressed on activated TH2 but not TH1 lymphocytes.
Hum Immunol. 2005 Dec;66(12):1223-34. Epub 2006 Mar 27.
PMID: 16690409 [PubMed - indexed for MEDLINE]
45: Lamason R, Zhao P, Rawat R, Davis A, Hall JC, Chae JJ, Agarwal R, Cohen P, Rosen A, Hoffman EP, Nagaraju K.
Sexual dimorphism in immune response genes as a function of puberty.
BMC Immunol. 2006 Feb 22;7:2.
PMID: 16504066 [PubMed - indexed for MEDLINE]
46: Zhao P, Hoffman EP.
Musculin isoforms and repression of MyoD in muscle regeneration.
Biochem Biophys Res Commun. 2006 Apr 14;342(3):835-42. Epub 2006 Feb 17.
PMID: 16500621 [PubMed - indexed for MEDLINE]
47: Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, Zhao P, Sartorelli V, Seo J, Pegoraro E, Angelini C, Shneiderman B, Escolar D, Chen YW, Winokur ST, Pachman LM, Fan C, Mandler R, Nevo Y, Gordon E, Zhu Y, Dong Y, Wang Y, Hoffman EP.
Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration.
Brain. 2006 Apr;129(Pt 4):996-1013. Epub 2006 Feb 14.
PMID: 16478798 [PubMed - indexed for MEDLINE]
48: Seo J, Gordish-Dressman H, Hoffman EP.
An interactive power analysis tool for microarray hypothesis testing and generation.
Bioinformatics. 2006 Apr 1;22(7):808-14. Epub 2006 Jan 17.
PMID: 16418236 [PubMed - indexed for MEDLINE]
49: Melcon G, Kozlov S, Cutler DA, Sullivan T, Hernandez L, Zhao P, Mitchell S, Nader G, Bakay M, Rottman JN, Hoffman EP, Stewart CL.
Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration.
Hum Mol Genet. 2006 Feb 15;15(4):637-51. Epub 2006 Jan 10.
PMID: 16403804 [PubMed - indexed for MEDLINE]
50: Wang Z, Wang Y, Xuan J, Dong Y, Bakay M, Feng Y, Clarke R, Hoffman EP.
Optimized multilayer perceptrons for molecular classification and diagnosis using genomic data.
Bioinformatics. 2006 Mar 15;22(6):755-61. Epub 2006 Jan 10.
PMID: 16403791 [PubMed - indexed for MEDLINE]
51: Byrnes KR, Garay J, Di Giovanni S, De Biase A, Knoblach SM, Hoffman EP, Movsesyan V, Faden AI.
Expression of two temporally distinct microglia-related gene clusters after spinal cord injury.
Glia. 2006 Mar;53(4):420-33.
PMID: 16345062 [PubMed - indexed for MEDLINE]
52: Hamed SA, Hoffman EP.
Automated sequence screening of the entire dystrophin cDNA in Duchenne dystrophy: point mutation detection.
Am J Med Genet B Neuropsychiatr Genet. 2006 Jan 5;141B(1):44-50.
PMID: 16331671 [PubMed - indexed for MEDLINE]
53: Zhao P, Caretti G, Mitchell S, McKeehan WL, Boskey AL, Pachman LM, Sartorelli V, Hoffman EP.
Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway.
J Biol Chem. 2006 Jan 6;281(1):429-38. Epub 2005 Nov 2.
PMID: 16267055 [PubMed - indexed for MEDLINE]
54: Urso ML, Clarkson PM, Hittel D, Hoffman EP, Thompson PD.
Changes in ubiquitin proteasome pathway gene expression in skeletal muscle with exercise and statins.
Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2560-6. Epub 2005 Oct 13.
PMID: 16224050 [PubMed - indexed for MEDLINE]
55: Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM.
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans.
Cell Metab. 2005 Oct;2(4):251-61.
PMID: 16213227 [PubMed - indexed for MEDLINE]
56: Molon A, Di Giovanni S, Hathout Y, Natale J, Hoffman EP.
Functional recovery of glycine receptors in spastic murine model of startle disease.
Neurobiol Dis. 2006 Feb;21(2):291-304. Epub 2005 Sep 22.
PMID: 16182553 [PubMed - indexed for MEDLINE]
57: Vanderver A, Schiffmann R, Timmons M, Kellersberger KA, Fabris D, Hoffman EP, Maletkovic J, Hathout Y.
Decreased asialotransferrin in cerebrospinal fluid of patients with childhood-onset ataxia and central nervous system hypomyelination/vanishing white matter disease.
Clin Chem. 2005 Nov;51(11):2031-42. Epub 2005 Sep 9.
PMID: 16155092 [PubMed - indexed for MEDLINE]
58: Chen YW, Nagaraju K, Bakay M, McIntyre O, Rawat R, Shi R, Hoffman EP.
Early onset of inflammation and later involvement of TGFbeta in Duchenne muscular dystrophy.
Neurology. 2005 Sep 27;65(6):826-34. Epub 2005 Aug 10.
PMID: 16093456 [PubMed - indexed for MEDLINE]
59: Gordon ES, Gordish Dressman HA, Hoffman EP.
The genetics of muscle atrophy and growth: the impact and implications of polymorphisms in animals and humans.
Int J Biochem Cell Biol. 2005 Oct;37(10):2064-74. Review.
PMID: 15967701 [PubMed - indexed for MEDLINE]
60: Hubal MJ, Gordish-Dressman H, Thompson PD, Price TB, Hoffman EP, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Clarkson PM.
Variability in muscle size and strength gain after unilateral resistance training.
Med Sci Sports Exerc. 2005 Jun;37(6):964-72.
PMID: 15947721 [PubMed - indexed for MEDLINE]
61: Gordon ES, Gordish-Dressman HA, Devaney J, Clarkson P, Thompson P, Gordon P, Pescatello LS, Hubal MJ, Pistilli EE, Gianetti G, Kelsey B, Hoffman EP.
Nondisease genetic testing: reporting of muscle SNPs shows effects on self-concept and health orientation scales.
Eur J Hum Genet. 2005 Sep;13(9):1047-54.
PMID: 15944650 [PubMed - indexed for MEDLINE]
62: De Biase A, Knoblach SM, Di Giovanni S, Fan C, Molon A, Hoffman EP, Faden AI.
Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity.
Physiol Genomics. 2005 Aug 11;22(3):368-81. Epub 2005 Jun 7.
PMID: 15942019 [PubMed - indexed for MEDLINE]
63: Fischer MD, Budak MT, Bakay M, Gorospe JR, Kjellgren D, Pedrosa-Domellöf F, Hoffman EP, Khurana TS.
Definition of the unique human extraocular muscle allotype by expression profiling.
Physiol Genomics. 2005 Aug 11;22(3):283-91. Epub 2005 Apr 26.
PMID: 15855387 [PubMed - indexed for MEDLINE]
64: Hittel DS, Hathout Y, Hoffman EP, Houmard JA.
Proteome analysis of skeletal muscle from obese and morbidly obese women.
Diabetes. 2005 May;54(5):1283-8.
PMID: 15855311 [PubMed - indexed for MEDLINE]
65: Clarkson PM, Hoffman EP, Zambraski E, Gordish-Dressman H, Kearns A, Hubal M, Harmon B, Devaney JM.
ACTN3 and MLCK genotype associations with exertional muscle damage.
J Appl Physiol. 2005 Aug;99(2):564-9. Epub 2005 Apr 7.
PMID: 15817725 [PubMed - indexed for MEDLINE]
66: Wu FF, Gordon E, Hoffman EP, Cannon SC.
A C-terminal skeletal muscle sodium channel mutation associated with myotonia disrupts fast inactivation.
J Physiol. 2005 Jun 1;565(Pt 2):371-80. Epub 2005 Mar 17.
PMID: 15774523 [PubMed - indexed for MEDLINE]
67: Fisher I, Abraham D, Bouri K, Hoffman EP, Muntoni F, Morgan J.
Prednisolone-induced changes in dystrophic skeletal muscle.
FASEB J. 2005 May;19(7):834-6. Epub 2005 Feb 25. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P].
PMID: 15734791 [PubMed - indexed for MEDLINE]
68: Clarkson PM, Devaney JM, Gordish-Dressman H, Thompson PD, Hubal MJ, Urso M, Price TB, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Hoffman EP.
ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women.
J Appl Physiol. 2005 Jul;99(1):154-63. Epub 2005 Feb 17.
PMID: 15718405 [PubMed - indexed for MEDLINE]
69: Nazarian J, Bouri K, Hoffman EP.
Intracellular expression profiling by laser capture microdissection: three novel components of the neuromuscular junction.
Physiol Genomics. 2005 Mar 21;21(1):70-80. Epub 2004 Dec 28.
PMID: 15623565 [PubMed - indexed for MEDLINE]
70: Di Giovanni S, Faden AI, Yakovlev A, Duke-Cohan JS, Finn T, Thouin M, Knoblach S, De Biase A, Bregman BS, Hoffman EP.
Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth.
FASEB J. 2005 Jan;19(1):153-4. Epub 2004 Nov 2.
PMID: 15522907 [PubMed - indexed for MEDLINE]
71: Di Giovanni S, De Biase A, Yakovlev A, Finn T, Beers J, Hoffman EP, Faden AI.
In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury.
J Biol Chem. 2005 Jan 21;280(3):2084-91. Epub 2004 Nov 1.
PMID: 15522871 [PubMed - indexed for MEDLINE]
72: Hittel DS, Kraus WE, Tanner CJ, Houmard JA, Hoffman EP.
Exercise training increases electron and substrate shuttling proteins in muscle of overweight men and women with the metabolic syndrome.
J Appl Physiol. 2005 Jan;98(1):168-79. Epub 2004 Sep 3.
PMID: 15347626 [PubMed - indexed for MEDLINE]